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GHK-Cu downregulates acute-phase and pro-inflammatory cytokines (TNF-?, IL-6), upregulates anti-oxidant defenses (including superoxide dismutase, Nrf2 and HO-1 pathways), and suppresses fibrotic signaling by inhibiting TGF-?1/Smad2/3 activation

سيروم النياسيناميد

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Methods: Retrospective screening of patients of the University Medical Centre Leipzig identified a cohort of 234 patients with chronic unexplained cholestasis